As part of ABS-CBN’s celebration of 60 years of Philippine television, the Kapamilya network offers another masterpiece with “Huwag Ka Lang Mawawala,” where Judy Ann Santos plays the role of Anessa Panaligan, a strong woman and loving daughter who will do everything for the sake of her family. Also part of the cast are Sam Milby, KC Concepcion, John Estrada, Tirso Cruz III, Coney Reyes, Susan Africa, Mylene Dizon, Matet De Leon, Empress, Bryan Termulo and Joseph Marco.

Anessa, a simple girl, falls for Eros (Sam), a rich young man who turns her life into a nightmare. Anessa belatedly finds out that Eros has a violent streak sparked by his obsessive love for her.

Romulus (Tirso) and Helena (Coney), her in-laws, refuse to accept her as their son's wife and favor Alexis, Eros' childhood best friend.

Anessa decides to escape Eros' clutches, along with their child Emman. In the process, she discovers that Eros is part of an illegal diamond smuggling operation. A police agent, Alejo (John), takes her into custody as a witness against Eros.

Anessa and Emman are trapped by Eros, and Anessa ends up being shot. Eros takes Emman to New York, and starts a new life with Alexis (KC).

While presumed dead by her family and her in laws, Anessa is actually alive. A kind doctor helps Anessa transform into an educated sophisticate, who will do everything to get the bittersweet taste of revenge against everyone who tried to bring her down.