Based on the longest-running Pinoy komiks series written by Jim Fernandez, Galema : Anak ni Zuma is an extraordinary tale about family and love. It will revolve around the life of a good-hearted young lady named Galema (Andi Eigenmann) who was born with twin snakes attached to her neck.

Andi plays the role of Galema, the daughter of Zuma (Derick Hubalde) who is a mythical creature with a twin two headed serpent rested on his shoulder to a human named Galela (Sheryl Cruz). Just like her father she inherited the twin two headed snake in her shoulder that made her mother and the rest of their family disgust her. But not with Isabel (Sunshine Cruz) who stood up to be her mother and tries everything to be normal for her. Matteo played the role of Morgan who became her good friend and later love interest. 

Also featured in Galema: Anak ni Zuma were Sunshine Cruz, Sheryl Cruz, Carlos Morales, Divina Valencia, Lito Legaspi, Joey Paras, Dante Ponce, Bryan Santos, and Meg Imperial.

It is directed by the box office director Wenn V Deramas.